DNA origami vaccine rivals mRNA shots while being easier to store and manufacture

The COVID-19 pandemic brought messenger RNA (mRNA) vaccines to the forefront of global health care. After their clinical ...

How a protein pair ensures that faulty mRNA is destroyed

Nonsense-mediated mRNA decay (NMD) is one of the most important processes in our cells to ensure that no faulty or incomplete proteins are produced. Scientists have now identified a central mechanism ...

Scientists Discover Simple Trick That Boosts mRNA Therapy Delivery 20-Fold

Lipid nanoparticles, or LNPs, are best known as the delivery system used in the COVID-19 mRNA vaccines given to billions of people worldwide. Scientists are now exploring their potential far beyond ...
Nature

‘Virtual cell’ captures most-basic process of life: bacterial division

Researchers simulated nearly every molecule in a bacterial cell — and then watched the cell grow and reproduce.

Why simulating an entire cell cycle took years, multiple GPUs and six days per run

By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell division—scientists have opened a new frontier of computer vision into the ...